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Antibiotic Resistance Perspective

 
 
  • ESCMID 2025 Read clinically focused news coverage of key developments from ESCMID 2025
  • Rapid PCR Testing Shows Mixed Results in Pneumonia Care Rapid syndromic polymerase chain reaction testing in the ICU vs standard-of-care testing improves antibiotic stewardship but fails to demonstrate non-inferiority in the clinical cure of pneumonia within 14 days.
  • Antibiotics Getting False Blame for Colitis, Study Finds A nationwide study of older adults in Sweden suggests a suspected link between antibiotic use and microscopic colitis is more likely a detection bias arising from similar gastrointestinal symptoms.
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  • Long or Short Antibiotics? Seniors Get Same Results Longer antibiotic courses showed no increased benefits or harms than shorter antibiotic courses in older adults, found a retrospective population-based cohort study.
  • First-Line Antibiotics Remain Best for UTI Treatment First-line antibiotics for uncomplicated UTI remain more effective than fluoroquinolones and beta-lactams in a retrospective cohort analysis.
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  • Early PDAT Shows Promise for Bacteremia Early phenotype-desirable antimicrobial therapy improved 30-day clinical outcomes in Enterobacterales bloodstream infections, highlighting its benefits for antimicrobial stewardship and patient care.
  • Doxycycline Postexposure Prophylaxis (Doxy PEP): 5 Things to Know Dr Jessica A. Penney and Sherry Chen at the Centers for Disease Control and Prevention provide guidance on Doxy PEP for STI prevention.
  • Klebsiella oxytoca: A Rising Challenge in Neonatal Care An outbreak of K oxytoca infections in Mexico has claimed 13 lives, highlighting the lethal potential of this gram-negative pathogen in clinical settings.
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  • Hypermucoviscous K pneumoniae Shows Reduced Drug Resistance Extended-spectrum beta-lactamase production and carbapenem resistance were less prevalent in hypermucoviscous K pneumoniae strains than in non-hypermucoviscous ones.
  • Imipenem-Cilastatin-Relebactam, the New Go-To for Pneumonia? Imipenem-cilastatin-relebactam matches piperacillin-tazobactam for hospital- or ventilator-acquired bacterial pneumonia, with similar safety, supporting use in areas with high multidrug resistance.
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  • Virtual UTI Care Linked to Rising Antibiotic Use From 2015 to 2022 the rate of antibiotic dispensation for UTIs climbed by 227.3% per 1000 patients, outpacing the 159.8% increase in positive urine cultures.
  • UTI in Primary Care: New Guidelines   The latest evidence-based recommendations for diagnosis, treatment, and prevention of recurrent UTI are reviewed here.
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  • Smaller Children Hit Harder by Antibiotic Mishaps The authors recommended taking child weight into account for prescriptions.
  • New Strategy Led to Modest Decline in Antibiotic Misuse A new study found a modest reduction in unnecessary antibiotic prescriptions for community-acquired infections following a multifaceted intervention.
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  • Do Antibiotics Worsen Lung Immunity During Flu? In hospitalized patients, eosinophil levels positively correlated with antibiotic use, systemic inflammation, and worsened outcomes.
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  • EPH 2024 Read clinically focused news coverage of key developments from EPH 2024
  • Rising Mycoplasma pneumoniae Cases in Young Children Medscape Medical News spoke with the CDC's Adam L. Cohen, MD, MPH, about what healthcare providers need to know about the increased number and severity of cases in young patients in the United States.
  • H pylori: ACG Guideline Advises New Approaches to Treatment The guideline drew on substantial new findings in regard to both the diagnosis and treatment of this common infection.
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  • IDWeek 2024 Read clinically focused news coverage of key developments from IDWeek 2024
  • Antibiotics Early in Life Linked to Childhood Atopy Evidence suggested causation in a study that controlled for multiple confounders.
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