Nephrology News

 
 
  • NKF 2025 Sparsentan Provides Better Proteinuria Reduction in FSGS A post-hoc analysis of the DUPLEX trial shows significantly greater improvements in proteinuria-related outcomes vs irbesartan for tough-to-treat FSGS.
  • NKF 2025 Chlorthalidone Increases Kidney Stone Recurrence A secondary analysis of the DCP shows that, compared with hydrochlorothiazide, chlorthalidone significantly increases the risk of kidney stones — but only among those with prior stones.
  • ATTD 2025 GLP-1s Eyed as Key to Managing T1D With Obesity As obesity rates rise among individuals with T1D, GLP-1 agonist medications, indicated for T2D and weight loss, are increasingly viewed as adjuncts to insulin.
  • Popular Joint Supplement Cuts Nephropathy Risk in T2D People with type 2 diabetes who regularly use the supplement glucosamine have a lower risk for microvascular complications and diabetic nephropathy, a prospective observational study finds.
  • Alert NICE Backs Oral Drug for Advanced Bladder Cancer NICE has approved the oral drug erdafitinib for adults with advanced urothelial cancer and FGFR3 alterations, offering new hope and home-based treatment.
  • Inflammatory Marker Predicts Liver Cancer Risk in T2D An inflammatory biomarker, YKL-40, serves as a reliable prognostic marker for liver and bladder cancers in patients with newly diagnosed T2D, outperforming CRP for these cancers.
  • AAN 2025 AI-Powered Wearable Calms Essential Tremor The Felix NeuroAI wristband delivers tailored and dynamic electrical stimulation to the ulnar, median, and radial nerves throughout the day to relieve essential tremor.
  • Experts Push Back on RFK Jr’s Infection Comments The new Secretary of Health and Human Services has made claims about measles and other communicable diseases that could lead to sickness, and even death, his critics claim.
  • ACC 2025 Private Equity Booms in Cardiology The cost of heart disease and high-priced procedures are fueling a surge in private equity–acquired cardiovascular outpatient practices and experts discuss how this is affecting patients.
  • ACC 2025 Novel Drug Moving Forward for Lp(a) A single dose of an siRNA molecule reduces elevated lipoprotein(a) — a major, but to date, largely untreatable risk factor for cardiovascular disease — a phase 2 trial shows.
  • ACC 2025 No Need to Restrict Fluids in Stable Heart Failure New evidence contradicts decades-old advice and shows that unlimited fluids are safe and ease discomfort from thirst.
  • FDA Approves New Treatment for Serious Kidney Disorder A new drug has received a quick federal nod for adults with a serious kidney disorder known as primary immunoglobulin A nephropathy.
  • What Else Can GLP-1 Drugs Do for Your Patients? How GLP-1 analogs are reshaping diabetes care and obesity treatment and unlocking potential in cardiovascular, inflammatory, and neurological diseases.
  • Alert FDA Approves First and Only Therapy for IgG4-RD The CD19+ B-Cell targeted therapy reduced flare risk by 87% in a phase 3 clinical trial.
  • How Office Props Improve Patient Outcomes Showing patients props and other visual aids improves recall of information, motivates patients, said doctors who have expanded their ‘black bags.’
  • Second Pig Kidney Transplant Success and FDA Trial Approval Previous skepticism turns to optimism as the first clinical trials for transplantation with genetically edited pig kidneys gain FDA approval.
  • Anifrolumab May Reduce Long-Term Organ Damage in Lupus Anifrolumab can substantially lower the risk for long-term organ damage progression in patients with moderate to severe active lupus, a retrospective study shows.
  • Obesity ‘Strongly’ Linked to 16 Cardiometabolic Diseases The prevalence of metabolic dysfunction–associated steatotic liver disease, chronic kidney disease, and obstructive sleep apnea, among others, increases with increasing BMI.
  • Thyroid Dysfunction Can Damage Kidneys in Kids With Obesity Children with obesity and subclinical hypothyroidism have twice the risk for kidney damage compared with those without subclinical hypothyroidism, a retrospective study shows.
  • Alert FDA Okays Perioperative Durvalumab for Bladder Cancer Approval was based on improved survival outcomes vs platinum-based chemotherapy as demonstrated in the phase 3 NIAGARA study.