Cardiovascular Risk: News

• ACC 2025 Rivaroxaban Comparable to Warfarin for LV Thrombus Post-MI The direct oral anticoagulant is an effective alternative to warfarin that offers predictable dosing without the need for routine monitoring in patients with STEMI, the RIVAWAR trial shows.
  Medscape Medical News, April 10, 2025
• ACC 2025 Novel Drug Moving Forward for Lp(a) A single dose of an siRNA molecule reduces elevated lipoprotein(a) — a major, but to date, largely untreatable risk factor for cardiovascular disease — a phase 2 trial shows.
  Medscape Medical News, April 08, 2025
• What Else Can GLP-1 Drugs Do for Your Patients? How GLP-1 analogs are reshaping diabetes care and obesity treatment and unlocking potential in cardiovascular, inflammatory, and neurological diseases.
  Medscape Medical News, April 07, 2025
• ACC 2025 WARRIOR Underscores Burden of Nonobstructive Angina in Women Because the trial ended up being underpowered, it did not show a benefit of intensive medical treatment, but there was a high rate of hospitalization in this population, which is not well understood.
  Medscape Medical News, April 04, 2025
• ACC 2025 SGLT2 Inhibitors Progressing to New Standard After TAVI In patients with heart failure, SGLT2 inhibitors after TAVI are associated with major risk reductions in a clinical trial that multiple experts are calling practice changing.
  Medscape Medical News, April 03, 2025
• Tips for PCPs on Addressing and Preventing Heart Disease Cardiac illnesses are among the trickier ones to manage in the limited time provided for many primary care visits, with common and easily dismissed symptoms often providing early signs of disease.
  Medscape Medical News, April 03, 2025
• Midlife Atrial Fibrillation Linked to Dementia Risk Atrial fibrillation diagnosed before age 70 years was associated with a 21% increased risk for dementia and a 36% increased risk for early-onset dementia in a large population-based study.
  Medscape Medical News, April 03, 2025
• Lower LDL of ‘Critical Importance’ in Reducing Dementia Risk LDL levels below 70 mg/dL are tied to a lower risk of developing dementia in general and Alzheimer’s disease-related dementia in particular.
  Medscape Medical News, April 02, 2025
• Obesity ‘Strongly’ Linked to 16 Cardiometabolic Diseases The prevalence of metabolic dysfunction–associated steatotic liver disease, chronic kidney disease, and obstructive sleep apnea, among others, increases with increasing BMI.
  Medscape Medical News, April 02, 2025
• Intermittent Fasting Beats Calorie Cutting for Weight Loss A 4:3 nonconsecutive intermittent fasting regimen was more tolerable and yielded somewhat greater weight loss at 1 year than daily caloric restriction.
  Medscape Medical News, April 02, 2025
• More Children Gaining Unhealthy Weight in Primary School More children in England are gaining excess weight during primary school than improving their BMI, a government analysis found.
  Medscape News UK, April 01, 2025
• ACC 2025 Does Treating Iron Deficiency in Heart Failure Help? A new study lacked significant results, but when combined with additional studies, the prevention of cardiovascular events was significant.
  Medscape Medical News, April 01, 2025
• ACC 2025 Clopidogrel Better Than Aspirin Long-Term After PCI Two years after percutaneous coronary intervention, people at risk of a cardiac event had better outcomes with clopidogrel maintenance therapy than with aspirin in the SMART-CHOICE 3 trial.
  Medscape Medical News, March 31, 2025
• ACC 2025 Oral GLP-1 Receptor Agonist Reduces CV Risk Oral semaglutide, already approved for type 2 diabetes, led to a reduction in CV events in patients with established atherosclerotic disease, CKD, or both.
  Medscape Medical News, March 30, 2025
• ACC 2025 Semaglutide Shows Major Benefits in PAD: STRIDE The GLP-1 agonist has shown convincing benefits in yet another population, patients with peripheral arterial disease, in a practice-changing trial, according to experts.
  Medscape Medical News, March 30, 2025
• ACC 2025 New Smartwatch Metric Points to Overall Heart Health A Northwestern medical student has found a better way of measuring heart health by smartwatch using a formula of steps per day and heart rate data.
  Medscape Medical News, March 29, 2025
• Alert Benefits Outweigh Risks for Weight Loss Drug Mysimba The benefits of naltrexone/bupropion (Mysimba) continue to outweigh its risks, despite ongoing uncertainty about long-term cardiovascular safety, the EMA says.
  Medscape Medical News, March 28, 2025
• ACC 2025 HPV Infection May Raise Risk for Cardiovascular Disease A meta-analysis offers insights on screening and prevention for high-risk patients.
  Medscape Medical News, March 28, 2025
• ACC 2025 Two New Studies Link Cannabis to Cardiovascular Problems A large retrospective study finds cannabis users have six times the risk for heart attacks. Meanwhile, a meta-analysis links the drug to a 50% increased risk for a heart attack.
  Medscape Medical News, March 26, 2025
• Alert FDA Expands Vutrisiran Indication to ATTR-Cardiomyopathy The FDA has approved a supplemental new drug application for the treatment of cardiomyopathy wild-type or hereditary transthyretin-mediated amyloidosis.
  Medscape Medical News, March 21, 2025