Heart Failure: Journal Articles

 
 
  • Accelerometer-Measured Sedentary Behavior and Risk of CVD A study of the association between accelerometer-measured sedentary behavior with risk of specific CV outcomes, including potential relations with moderate to vigorous physical activity
  • Nonpharmacologic Management of Patients With HF A review of the optimal lifestyle recommendations including dietary interventions, exercise, and management of sleep-disordered breathing, mood disorders, and substance use.
  • Valve Choice for TAVR: Much Left to re-SOLVE Elderly patients may fare similarly with either an SEV or a BEV, but for lifetime management in younger and/or lower-surgical-risk patients, relevant differences exist between the 2 platforms.
  • Responder Analyses Can Be Misleading The authors propose that anchor based analyses of continuous variable endpoints should be used to evaluate the clinical meaningfulness of observed treatment effects in clinical trials.
  • Revisiting ICDs for Primary Prevention in HFrEF A review of the data underpinning guideline recommendations for implantable cardioverter-defibrillators (ICDs) to reduce the risk of SCD in patients with HFrEF and pragmatic guidance for clinicians.
  • MRAs in HF: Established and Emerging Roles A comprehensive review of the current data on MRAs for HF and the future direction of nonsteroidal MRA research, that also explores the causes of MRA underutilization.
  • Consequences of Discontinuing Long-Term Drugs in HFrEF Currently patients with HF are prescribed many drugs for their lifetime. This paper reviews strategies to assess whether efficacy persists and the potential consequences of discontinuation.
  • Cardiac Myosin Inhibitors: Is the Emperor Wearing Any Clothes? A commentary on the need for better trials and long-term data for the myosin inhibitors aficamten and mavacamten in obstructive hypertrophic cardiomyopathy.
  • Heart Failure Drug Development Over the Eras A summary of current efforts of the Heart Failure Collaboratory that highlights important concepts in the contemporary landscape of HF drug development.
  • Takeaways From Six Substudies of the Semaglutide Trials A summary of findings from the 6 Substudies of the SELECT, STEP-HFpEF, and FLOW Trials
  • HF Risk Assessment Using Biomarkers in Patients With AF An analysis from COMBINE-Af on the incremental prognostic performance of NT-proBNP, hs-cTnT, and GDF-15 for HF risk stratification in patients with AF.
  • Distinct Comorbidity Clusters in Patients With Acute HF Five distinct multimorbidity groups were identified from the RELAX-AHF-2 trial population, showing variations in clinical outcomes.
  • Temporal Trends in Takotsubo Syndrome An analysis of nearly 4,000 cases of Takotsubo syndrome from the InterTAK registry.
  • Obesity and Weight Loss Strategies in Heart Failure A review of published data on the epidemiology of obesity and HF, the rationale and caveats regarding intentional weight loss for patients with HF across lifestyle, surgical, and medication domains.
  • Patch Wearable Defibrillator Works, If Patients Stick With It The Jewel IDE trial supports the use of a water-resistant wearable cardioverter-defibrillator patch in adults at risk for sudden cardiac arrest; however 38% of patients exited the study early..
  • Stable Angina: A Patient-Centered Approach A review of the complementary role of coronary revascularization, optimal medical therapy, and lifestyle interventions in the management of stable angina, and the importance of an approach that targets the pathobiology.
  • Contemporary In-Hospital Decongestion Strategies in HF A large-scale U.S. community-based cohort study of HF hospitalizations reviews contemporary inpatient diuretic practices and clinical predictors of weight loss.
  • HDL Parameters and Risk of Heart Failure The association between HDL particle concentration and size with heart failure is studied in participants from the ARIC, MESA, PREVEND, and Dallas Heart studies.
  • To Stent or Not to Stent in Ischemic Heart Failure Does percutaneous coronary intervention improve clinical outcomes in patients with severe left ventricular dysfunction?
  • Acute Liver Failure Due to Herpes Simplex Viral Hepatitis While a rare occurrence, this case underscores the need to be aware of HSV hepatitis as a possible cause of acute liver failure.