Heart Failure: Perspectives

 
 
  • Apr 11 2025 This Week in Cardiology  
  • ACC 2025 Little Learned From Trials That Are Positive by Design Dapagliflozin after TAVI? Semaglutide for claudication? Two trials designed to be positive should not warrant new indications for these drugs writes John Mandrola, MD.
  • FDA Drug Approvals Q1 2025 Stay current on FDA drug approvals January-March 2025
  • ACC 2025 Fluid Restriction in HF: Let’s Not Torture Patients   Drs Piña and Hsich discuss the FRESH-UP trial that challenged the dogma of fluid restriction in heart failure and provide practical strategies for optimizing medical therapy instead.
  • Apr 04 2025 This Week in Cardiology   Trials from the 2025 American College of Cardiology scientific sessions, including the WARRIOR, PROTECT TAVI, DAPATAVI, and SOUL are reviewed by John Mandrola, MD
  • Should Medicine Be Boring? Heroic high-stakes medicine should be left to TV doctors, because the most effective care is performed with a level of precision bordering on the mechanical and the mundane.
  • Mar 28 2025 This Week in Cardiology   Stopping oral anticoagulation after AF ablation, the core problem with paradoxes like the smoker’s paradox, chronic total occlusion PCI, and an ACC/EHRA preview are discussed by John Mandrola, MD, in this week’s podcast.
  • Counteracting Mineralocorticoid Receptor Activation in CVD   Mineralocorticoid receptor overactivation increases the risk for serious cardiovascular events through a diverse range of harmful yet preventable actions, as discussed by leading cardiologists.
  • ACC 2025 Read clinically focused news coverage of key developments from ACC 2025
  • ACC 2025 Mandrola’s 5 Picks for ACC 25 Trials on cerebral protection in TAVR, fluid restriction in heart failure, and risk factor management in AF are among John Mandrola’s picks from the upcoming ACC Scientific Sessions.
  • S3 Episode 3: The 2025 updates of the American Diabetes Association   Drs Carol H. Wysham and Rozalina G. McCoy discuss the 2025 updates of the American Diabetes Association, including comorbidities, dental care, sexual dysfunction, and CGM use.
  • Mar 21 2025 This Week in Cardiology   A large trial in cardiac pacing finally published, PVCs and cardiomyopathy, cannabis, CV risk and the danger of observational studies, and the tale of two disparate statin trials are the topics John Mandrola, MD, discusses in this week’s podcast.
  • Mar 14 2025 This Week in Cardiology   Listener feedback, resistant hypertension, K-binders for MRA use in heart failure, nutritional epidemiology, and a positive study for vitamin D are the topics John Mandrola, MD, discusses in this week’s podcast.
  • ECIM 2025 Read clinically focused news coverage of key developments from ECIM 2025
  • Mar 07 2025 This Week in Cardiology   Listener feedback on asymptomatic aortic stenosis (AS), transcatheter aortic valve replacement (TAVR) vs surgical aortic valve replacement (SAVR), coronary artery calcium (CAC), and revascularization for patients with ischemic LV dysfunction are discussed by John Mandrola, MD, in today's podcast.
  • Cardiovascular Risk in Non–Dialysis-Dependent CKD Patients   Chronic kidney disease (CKD) increases risk for serious cardiovascular (CV) events. Drs Sankar Navaneethan and Holly Kramer discuss strategies to reduce CV risk in non–dialysis-dependent CKD patients.
  • S2 Episode 1: What's Next? Clinical Trials in Myelofibrosis   Drs Tania Jain and Ruben Mesa discuss the clinical trials and the future of myelofibrosis research.
  • GLP-1 Drugs Offer More Than Weight Loss and Glucose Control   Dr Priya Jaisinghani discusses the benefits of GLP-1 therapy beyond glycemic control and weight management.
  • Feb 28 2025 This Week in Cardiology   The treatment of asymptomatic aortic stenosis, the move to composite endpoints in trials, IFR vs FFR and high-frequency low tidal volume ventilation for AF ablation are the topics John Mandrola, MD, discusses in today's podcast.
  • Are We Inflating the Success Rate of AF Ablation? Not counting recurrent arrhythmias that occur during the 3-month blanking period after ablation for atrial fibrillation is fudging the numbers, writes electrophysiologist John Mandrola, MD.