Atrial Fibrillation: Perspective

 
 
  • Apr 11 2025 This Week in Cardiology  
  • ACC 2025 Little Learned From Trials That Are Positive by Design Dapagliflozin after TAVI? Semaglutide for claudication? Two trials designed to be positive should not warrant new indications for these drugs writes John Mandrola, MD.
  • Novel Blood Thinner Shows Promise in Atrial Fibrillation A recent study reveals that asundexian may reduce the risk for stroke and bleeding in patients with atrial fibrillation and limited prior anticoagulant exposure.
  • Mar 28 2025 This Week in Cardiology   Stopping oral anticoagulation after AF ablation, the core problem with paradoxes like the smoker’s paradox, chronic total occlusion PCI, and an ACC/EHRA preview are discussed by John Mandrola, MD, in this week’s podcast.
  • ACC 2025 Read clinically focused news coverage of key developments from ACC 2025
  • ACC 2025 Mandrola’s 5 Picks for ACC 25 Trials on cerebral protection in TAVR, fluid restriction in heart failure, and risk factor management in AF are among John Mandrola’s picks from the upcoming ACC Scientific Sessions.
  • Mar 21 2025 This Week in Cardiology   A large trial in cardiac pacing finally published, PVCs and cardiomyopathy, cannabis, CV risk and the danger of observational studies, and the tale of two disparate statin trials are the topics John Mandrola, MD, discusses in this week’s podcast.
  • Aggressive Ablation Better Than Regular for AF Aggressive ablation shows better clinical outcomes than regular ablation in patients with persistent atrial fibrillation.
  • Elevated BNP After AF Ablation Signals Future Risks Integrating pre- and postablation BNP levels in patients with persistent atrial fibrillation may facilitate risk stratification for major adverse cardiovascular events and arrhythmic recurrence.
  • Mar 07 2025 This Week in Cardiology   Listener feedback on asymptomatic aortic stenosis (AS), transcatheter aortic valve replacement (TAVR) vs surgical aortic valve replacement (SAVR), coronary artery calcium (CAC), and revascularization for patients with ischemic LV dysfunction are discussed by John Mandrola, MD, in today's podcast.
  • NT-proBNP May Predict Atrial Fibrillation Risk Early Incorporating NT-proBNP, a biomarker for heart failure, into traditional risk prediction models for atrial fibrillation may enhance early detection in individuals at risk for the condition, according to a systematic review and meta-analysis of cohort studies.
  • Feb 28 2025 This Week in Cardiology   The treatment of asymptomatic aortic stenosis, the move to composite endpoints in trials, IFR vs FFR and high-frequency low tidal volume ventilation for AF ablation are the topics John Mandrola, MD, discusses in today's podcast.
  • Are We Inflating the Success Rate of AF Ablation? Not counting recurrent arrhythmias that occur during the 3-month blanking period after ablation for atrial fibrillation is fudging the numbers, writes electrophysiologist John Mandrola, MD.
  • Transseptal Approach Shields Brain During Ablation For patients undergoing left ventricular catheter ablation, the occurrence of acute brain lesions is lower with a transseptal puncture than with a retrograde aortic approach.
  • Hot Topics From the International Stroke Conference   Prof Christoph Diener picks his top trials from the 2025 International Stroke Conference covering thrombectomy for distal stroke, thrombolysis timing, and anticoagulation options in AF.
  • Feb 21 2025 This Week in Cardiology   Blanking period after AF ablation, periprocedural MI after PCI in non-STEMI, predicting AF after ischemic stroke, and the proper standards for mitral valve repair in primary mitral regurgitation are the topics John Mandrola, MD, discusses in today’s podcast.
  • ECG Challenge: What's Causing This Patient's Palpitations? A 55-year-old woman presents with classic signs of hyperthyroidism. But what else is going on?
  • Feb 14 2025 This Week in Cardiology   Silent cerebral embolism after LAAC, AI in ECG rhythm analysis, anti-thrombotic strategies in patients with AF and CAD, and subclinical AF are the topics John Mandrola, MD, covers in today's podcast.
  • Feb 07 2025 This Week in Cardiology   Sugar-sweetened beverages, the epidemiology of driving after an ICD, BP measurements, and massive EBM lesson in EVT for acute stroke are the topics John Mandrola, MD, discusses in today's podcast.
  • HFpEF in Primary Care: Best Pharmacotherapy   The Curbsiders address the primary care management of heart failure with preserved ejection fraction, with tips from esteemed expert Dr Michelle Kittleson.