Hypothalamic, Pituitary, and Adrenal Disorders Articles

• Sucralose Affects Brain Mechanisms That Regulate Appetite The noncaloric sweetener sucralose appears to influence how the hypothalamus interprets sweet taste and metabolic signals, potentially influencing appetite regulation over time.
  Medscape Medical News, April 10, 2025
• Rhythm Pharma's Drug for Rare Obesity Meets Late-stage Trial Goal Rhythm Pharmaceuticals said on Monday its drug Imcivree notably reduced weight in patients with a rare obesity disorder caused by damage to the brain, meeting the main goal...
  Reuters Health Information, April 07, 2025
• Routine Adrenal Testing Post-Prednisolone May Not Be Needed Only 1.9% of patients show glucocorticoid-induced adrenal insufficiency after discontinuing prednisolone, indicating that routine adrenal function testing with a short corticotropin test is unnecessary.
  Medscape News UK, March 25, 2025
• Immune Checkpoint Inhibitors Cause of Type 1 Diabetes?   Dr Anne Peters discusses immune checkpoint inhibitor–induced type 1 diabetes and the priorities in managing patient care.
  Medscape Diabetes & Endocrinology, March 20, 2025
• Male Bone Health at Risk in Congenital Adrenal Hyperplasia Boys and young adult male patients with congenital adrenal hyperplasia receiving glucocorticoid treatment have lower bone mineral density than healthy individuals, an Italian study shows.
  Medscape News UK, March 04, 2025
• Alert ‘Game Changer’ Approved for Congenital Adrenal Hyperplasia The US Food and Drug Administration has approved crinecerfont for treating congenital CAH in combination with glucocorticoids.
  Medscape Medical News, December 17, 2024
• Low Bone Strength Even After Remission in Cushing Syndrome Bone material strength index values were found to be low in patients with Cushing syndrome even after long-term remission, indicating persistent impairment of tissue-level bone properties.
  Medscape Medical News, December 09, 2024
• Growth Hormone and the Thyroid Gland: A Complex Relationship   Drs Kaniksha Desai and Laurence Katznelson discuss the complex relationship between growth hormone and the thyroid gland.
  American Thyroid Association, November 26, 2024
• Anastrozole Increases Height in Children With CAH In children with congenital adrenal hyperplasia, anastrozole treatment increased the predicted adult height by 13 cm in girls and 17 cm in boys over 6 years.
  Medscape Medical News, November 22, 2024
• Patients With Cushing Syndrome Face Higher Glaucoma Risk Patients with endogenous Cushing syndrome faced an increased risk for glaucoma at a younger age than is typical for the eye disorder, a retrospective analysis found.
  Medscape Medical News, November 13, 2024
• ‘Round Face’: A Viral Term’s Real Diagnostic Implications Popular videos and social media posts have identified cortisol as the main culprit behind facial puffiness, but many disorders can underlie such symptoms. Here’s how to diagnose them.
  Medscape Medical News, November 11, 2024
• Autoimmune Diseases and Premature Ovarian Insufficiency The study results strengthen the hypothesis that autoimmune mechanisms play an important role in the pathogenesis of premature ovarian insufficiency.
  Medscape Medical News, October 02, 2024
• A New Focus for Cushing Syndrome Screening in Obesity Screening for Cushing syndrome in patients with obesity revealed a low prevalence, with nearly all the risk for the rare endocrine disorder in the metabolically unhealthy obesity phenotype.
  Medscape Medical News, September 06, 2024
• NICE: Give People With Adrenal Insufficiency Emergency Kits People with adrenal insufficiency should be given emergency kits to help avoid hospital admission, said NICE in its new clinical guideline.
  Medscape News UK, August 28, 2024
• Steps to Take for Diagnosing Cushing Syndrome Your patient's "round face" might be the first clue that he or she has Cushing syndrome, but there are other symptoms as well. How can you accurately diagnose the condition?
  Medscape Medical News, August 23, 2024
• Gender and Sports: Can Science Enable Fair Competition? The allegations against Algerian boxer Imane Khelif raised the complicated question of intersexuality and its implications for competitive sports.
  Medscape Medical News, August 20, 2024
• Cyclic Vomiting Syndrome: Practice Update Guides Dx, Mgmt CVS affects up to 2% of US adults and is more common in women, young adults, and those with a personal or family history of migraine headaches.
  MDedge News, July 30, 2024
• EULAR 2024 Taper, Dose Down, Discontinue: Striving for Less Steroid Use Now in the 75th year since the first presentation on the clinical use of glucocorticoids, what consensus has been reached in sparing their use to avoid their many potential adverse effects?
  Medscape Medical News, July 25, 2024
• EULAR 2024 Breaking Rheumatology's Reliance on Steroids: New Strategies Selective GC receptor agonists and modulators and GC plus hydroxysteroid dehydrogenase inhibitor combination therapy are some of the approaches under consideration.
  Medscape Medical News, July 25, 2024
• ADA 2024 Hypercortisolism Prevalence High in Poorly Controlled T2D Investigators in the CATALYST trial said the findings suggest a potential paradigm shift in managing patients with uncontrolled diabetes.
  Medscape Medical News, June 28, 2024