At the 2025 Annual Meeting of the American Academy of Dermatology, Adam Friedman, MD, reports on key discussions centered around chronic spontaneous urticaria (CSU) and its management. He notes that while food can be linked to acute urticaria, it is unlikely to be a major cause of chronic cases. He also highlights the role of vitamin D supplementation in enhancing treatment efficacy. Additionally, he suggests that low-histamine and Mediterranean diets, along with vitamin D, may help manage CSU alongside traditional therapies like antihistamines and omalizumab.
Dr Friedman also reviews new research, including a study linking cytokines to disease activity, which may help identify future treatment targets for CSU. He further discusses studies on the cost burden of CSU treatments, emphasizing their significant impact on patients' lives. Exciting new therapeutic agents, such as remibrutinib, are showing promise in improving CSU symptoms, with more innovations expected soon.